Produced by Dr. Mark Brownfield, the peptide sequence encoding the rat GLP2R was retrieved from the NCBI protein database and evaluated using GeneRunner software to generate antigen candidates for antibody production. Antibody was generated in rabbits and purified by affinity chromatography against the antigenic peptide. The specificity of the antibody was confirmed by Western blotting and by immunoabsorption controls is the immunohistochemistry procedure (see Nelson et al, Endocrinology 148(5)1954-1962, 2007. The antiserum demonstrates significant labeling of enteroendocrine cells in the intestinal epithelium, as well as cell bodies of vagal afferents in nodose ganglia of the parasympathetic nervous system. Immunolabeling of Western blot revealed a band of approximately 66 kDa in human and rat tissue.
Photo Description: IHC image of enteroendocrine cells in the intestinal epithelium.Host: Rabbit
Quantity/Volume: 100 µL
State: Liquid
Reacts With: : RatAlternate Names: anti-GLP2RRRID: to be determinedImmunogen: GLP2R阿尔茨海默氏症协会称,阿尔茨海默氏症的研究抗体在帮助科学家找到解决这种疾病和其他痴呆症的方法方面发挥着重要作用,这些疾病和痴呆症影响了全世界4700万人和530万美国人,到2050年,这一数字有望增加两倍。随着婴儿潮一代的年龄增长,预计将有2800万人患上这种疾病,其费用将升至美国医疗保险总支出的近四分之一。
自从Aloysius Alzheimer博士于1906年首次描述这种疾病以来,科学家们在了解这种疾病如何影响大脑方面取得了显着进步。十多年后,理解和治疗的突破为阿尔茨海默氏病患者带来了希望。
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